RNA Details
Disease Name
aortic coarctation
Tissue
heart
RNA Symbol
mir-21
RNA ID
RNA Type
miRNA
Alteration Pattern
up regulation
Species
homo sapiens
Detection Methods
PCR; immunohistochemistry; Echocardiography
Target
NA
Pathway
NA
PubMed ID
Title
Myocardial and circulating levels of microRNA-21 reflect left ventricular fibrosis in aortic stenosis patients
Year
2013
Function
Plasmatic miR-21 in the maladaptive remodeling of the extracellular matrix induced by pressure overload in aortic stenosis (as) patients and the clinical value of miR-21 as a biomarker for pathological myocardial fibrosis.